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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFPT All Species: 20.91
Human Site: T246 Identified Species: 57.5
UniProt: P0C1Z6 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C1Z6 NP_037474.1 253 28278 T246 D K L L P Y P T L A S P A S D
Chimpanzee Pan troglodytes XP_001174783 244 27186 T237 D K L L P Y P T L A S P A S D
Rhesus Macaque Macaca mulatta XP_001116861 253 28221 T246 D K L L P Y P T L A S P A S D
Dog Lupus familis XP_854238 253 28269 T246 D K L L P Y P T L A S P P F D
Cat Felis silvestris
Mouse Mus musculus Q3U1J1 259 28935 T252 D K L L P Y P T L A S P P F D
Rat Rattus norvegicus Q9JMG6 259 28889 T252 D K L L P Y P T L A S P P F D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512352 253 28036 G246 D K L L Q Y P G L V S P P F D
Chicken Gallus gallus
Frog Xenopus laevis NP_001086435 252 28867 K245 D K I L Q Y P K F S S P D F D
Zebra Danio Brachydanio rerio NP_001154179 186 20727
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 98 95.2 N.A. 86.4 86.4 N.A. 81 N.A. 56.5 42.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.4 98.4 96 N.A. 88.4 88.4 N.A. 84.5 N.A. 69.9 54.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 66.6 N.A. 53.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 66.6 N.A. 66.6 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 67 0 0 34 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 89 0 0 0 0 0 0 0 0 0 0 0 12 0 89 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 0 0 0 56 0 % F
% Gly: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 89 0 0 0 0 0 12 0 0 0 0 0 0 0 % K
% Leu: 0 0 78 89 0 0 0 0 78 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 67 0 89 0 0 0 0 89 45 0 0 % P
% Gln: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 12 89 0 0 34 0 % S
% Thr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 89 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _